| About this Abstract |
| Meeting |
2020 TMS Annual Meeting & Exhibition
|
| Symposium
|
Biodegradable Materials for Medical Applications II
|
| Presentation Title |
B-6: Evaluation of Electrospinning Parameters for Fabrication of Biodegradable Drug Carrier Silk Fibers |
| Author(s) |
Babak Jahani, Sahar Tabatabaei , Salimeh Yasaei Sekeh, Long Jiang |
| On-Site Speaker (Planned) |
Babak Jahani |
| Abstract Scope |
Electrospinning is a standard and cost-effective method to produce fibers in the range of micrometer to nanometer. The main parameters affecting the morphology and diameters of electrospun fibers are viscosity and conductivity of solution, surface tension, applied voltage, tip to collector distance and the flow rate of solution from the needle tip to the collector. By tuning these parameters, electrospun fibers with desirable morphology and size can be achieved. In this study, silk fibers have been fabricated by electrospinning technique. Silk is a natural fiber contains two major proteins- hydrophobic fibroin and hydrophilic sericin. These fibers can be used as biocompatible and biodegradable drug carriers. The goal of this work is to experimentally evaluate the effect of each parameter of electrospinning process on the resultant electrospun fibers and also suggesting the optimized values for process parameters in order to satisfy the requirements of drug delivery applications. |
| Proceedings Inclusion? |
Planned: Supplemental Proceedings volume |