| Abstract Scope |
The success of biomedical implants hinges on the intricate interfaces between tissues and biomaterials, where nanoscale modifications can significantly enhance biocompatibility and device performance. These bio-nano interfaces are pivotal in regenerative medicine, facilitating cellular adhesion, proliferation, and differentiation. Techniques such as electrical charge modulation and nanostructured surface roughness improve implant integration into host tissues. The use of Masquelet membranes promotes vascularization and tissue ingrowth, crucial for large segmental defects. Tailoring the microenvironment, especially in conditions like diabetic bone, is essential for functional tissue restoration. Advanced biomaterial designs that direct biochemical signals and cellular interactions are opening new frontiers in tissue engineering. This talk will focus on multifaceted approaches, including interface-focused surface engineering and regenerative membrane formation, that significantly enhance clinical outcomes and patient quality of life in complex therapeutic scenarios. |