About this Abstract |
Meeting |
2025 TMS Annual Meeting & Exhibition
|
Symposium
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Structure-Property Relationships in Molecular Crystal Deformation
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Presentation Title |
Mechanical response of single crystal acetaminophen over an extended strain rate |
Author(s) |
Kyle J. Ramos, Cindy A Bolme, John Lazarz, Bryan Zuanetti, Milovan Zecevic, Tom Pilvelait, Marc Cawkwell |
On-Site Speaker (Planned) |
Kyle J. Ramos |
Abstract Scope |
Acetaminophen is an intriguing molecular crystalline material. As a prototypical pharmaceutical, its chemical, thermodynamic, and physical properties have been studied extensively. It exhibits a solid-solid phase transition between a stable monoclinic and metastable orthorhombic phase. The disparity between the tabletability of these phases is an application relevant research topic throughout literature. Because of these structural similarities with explosives and interest in its mechanical response under compaction, we have used acetaminophen as a less-hazardous stand in when developing and implementing techniques for studying explosives. Data has been accumulated on the optical, elastic, and elastic-plastic response over an extended strain rate for single crystal acetaminophen, which we will report and discuss. The data enables development of single crystal plasticity models for investigating mechanical response of interest to both pharmaceutical and explosive communities. |
Proceedings Inclusion? |
Planned: |
Keywords |
Mechanical Properties, Phase Transformations, Characterization |