| About this Abstract |
| Meeting |
MS&T22: Materials Science & Technology
|
| Symposium
|
Society for Biomaterials: Biological Response to Materials and Material’s Response to Biological Environments
|
| Presentation Title |
Effects of Debindering Temperature of Carbonate Apatite Honeycomb on Osteoconductivity |
| Author(s) |
Kunio Ishikawa, Keigo Shibahara, Koichiro Hayashi, Yasuharu Nakashima |
| On-Site Speaker (Planned) |
Kunio Ishikawa |
| Abstract Scope |
Carbonate apatite honeycomb (CO3Ap HC) artificial bone may be useful for the reconstruction of long bone defect. The honeycomb is fabricated by debindering the CaCO3-binder honeycomb followed by compositional transformation in Na2HPO4 aqueous solution. In this study, effects of debindering temperature (600°C, 650°C, 700°C) on physical properties and osteoconductivity were investigated. 10-mm length ulna defect of the rabbits were reconstructed with the CO3Ap HC. Micropore volume decreased with increase in debindering temperature. Compressive strength increased with debindering temperature, New bone bridging the existing bone and CO3Ap HC was observed regardless of the debindering temperature 4 weeks after surgery. Also, new bone penetrated inside the pore regardless of the debindering temperature 4 weeks after surgery. Length of the new bone from the existing bone was larger for CO3Ap HC debindered at lower temperature. It was concluded that micropore volume of the CO3Ap HC plays important roles for mechanical strength and osteoconductivity. |