| About this Abstract |
| Meeting |
2023 TMS Annual Meeting & Exhibition
|
| Symposium
|
Advances in Biomaterials for 3D Printing of Scaffolds and Tissues
|
| Presentation Title |
Investigation of Cell Sedimentation and Cell Aggregation during 3D Bioprinting |
| Author(s) |
Md Shahriar, Heqi Xu, Jiachen Liu, Changxue Xu, Dulce Martinez Salazar |
| On-Site Speaker (Planned) |
Md Shahriar |
| Abstract Scope |
Bioink, as an essential element for 3D bioprinting, is composed of biological materials and living cells. When the buoyant force is not sufficient to balance the gravitational force, the suspended cells are driven by dominant gravitational force to sediment and finally accumulate at the bottom of the bioink reservoir. With cell accumulation at the bottom of the bioink reservoir, the interaction and aggregation of cells are facilitated. Due to the cell sedimentation and aggregation, the uniformity of the cell distribution within the bioink reservoir is reduced and the printing performance is significantly affected. This study investigates the cell sedimentation velocities of individual cells, small cell aggregates, and large cell aggregates at different printing time. In addition, the percentages of cells forming different types of cell aggregates and the cell concentrations in different regions of the bioink reservoir are characterized at different printing time, respectively. |
| Proceedings Inclusion? |
Planned: Supplemental Proceedings volume |