About this Abstract |
Meeting |
MS&T24: Materials Science & Technology
|
Symposium
|
Next Generation Biomaterials
|
Presentation Title |
4th Generation of Magnetic Bioactive Glass-Ceramics: A New Nanocomposite With Improved Magnetic and Bioactivity Properties Aiming Magnetic Hyperthermia Application |
Author(s) |
Roger Borges, Francesco Baino, Juliana Marchi |
On-Site Speaker (Planned) |
Juliana Marchi |
Abstract Scope |
Magnetic bioactive glass-ceramics (MBGCs) are biomaterials applied for magnetic hyperthermia in bone cancer treatment, thereby treating the bone tumor besides regenerating the damaged bone. In this work, we overview the generations of the MBGCs considering some advances regarding saturation magnetization values and bioactivity properties. Optimizing both properties in a unique material remains a challenge since the thermal treatment step employed to grow magnetic phases is also related to loss of bioactivity. In this work, a new nanocomposite made of superparamagnetic iron oxide nanoparticles (SPIONs) dispersed in a sol-gel-derived bioactive glass matrix is presented. Using an innovative approach, it was possible to obtain a magnetic bioactive material with tunned both magnetical and bioactivity properties. Thereby, these nanocomposites can be recognized for the first time as the 4th generation class of bioactive materials for applications in bone cancer treatment by hyperthermia. |