| About this Abstract |
| Meeting |
2024 TMS Annual Meeting & Exhibition
|
| Symposium
|
Magnesium Technology 2024
|
| Presentation Title |
Bioabsorbable Magnesium Composite Sheared at High Temperatures for Use in Bone Implants |
| Author(s) |
Andres Larraza, Pedram Sotoudeh Bagha, Mehdi Razavi |
| On-Site Speaker (Planned) |
Andres Larraza |
| Abstract Scope |
Bioabsorbable magnesium composites have shown promise in improve bone regeneration. These materials aim to repair damaged bone as the material dissolves while being cleared via non-toxic pathways. High-shear mixing has recently been shown to effectively agitate metal matrix melts resulting in uniform composites. The uniformity of the composites results in improved mechanical properties and biocompatibility. In this study, magnesium/nanoceramic composites were prepared using a novel high-shear mixer. The effects on the material's microstructure, mechanical properties, corrosion resistance, cell viability, and osteogenic properties were studied. Biocompatibility and osteoinductivity were tested in rat models in vivo, and the results were analyzed histologically. Magnesium composites' properties can be enhanced through high-shear mixing, leading to better bone repair and regeneration and new possibilities for treating bone fractures and bone-related disorders. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Magnesium, Other |