| About this Abstract |
| Meeting |
2023 TMS Annual Meeting & Exhibition
|
| Symposium
|
Advanced Biomaterials for Biomedical Implants
|
| Presentation Title |
Candida Albicans Biofilm Formation of an Additive-manufactured Titanium Alloy |
| Author(s) |
Mari Koike, Tetsuro Horie, Richard J Mitchell, Susan K Hummel, Toru Okabe |
| On-Site Speaker (Planned) |
Mari Koike |
| Abstract Scope |
This study was to evaluate the biofilm accumulation of titanium alloys fabricated with additive manufacturing that have possessed desirable characteristics for biomedical applications. Disks (10 mm dia. x 2 mm thick) of Ti-6Al-4V alloy were fabricated with the following techniques: electron beam melting (EBM) or laser beam melting (LBM) by additive manufacturing (AM), or lost-wax technique using a centrifugal casting machine. Teflon® was used as controls. After sterilizing specimens, each specimen (n=6/condition) was placed in each well and incubated statically with Candida albicans (CA, ATCC MYA2876). After 48-hour, the viability of CA adhering to each specimen was determined using a bioluminescence assay. Ti-6Al-4V specimens made by AM showed less biofilm accumulation than the as-cast specimens. The surface of Ti specimens by EBM-AM are bumpier but smoother than the as-cast specimens. In this test period, it appears that surface roughness as measured by Sa does not correlate to biofilm accumulation. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Additive Manufacturing, Biomaterials, Titanium |