| About this Abstract |
| Meeting |
Materials Science & Technology 2020
|
| Symposium
|
Nanotechnology for Energy, Environment, Electronics, Healthcare and Industry
|
| Presentation Title |
Effect of CuO/MgO Ratio on the Gene Expression, Cytocompatibilty, and Antibacterial/Analgesic/ Anticancerous Drug Loading Kinetics for the Mesoporous Bioactive Glasses |
| Author(s) |
Gurbinder Kaur |
| On-Site Speaker (Planned) |
Gurbinder Kaur |
| Abstract Scope |
Controlled drug delivery is one of the most advancing research area of biomedical engineering. The drug delivery systems offer number of advantages over the conventional treatment. Targeted drug delivery using mesoporous bioactive glasses (MBGs) has opened new era for the bone tissue regeneration applications. Our group aims at fabricating novel (MBGs) using CTAB/P127/F123 as structure directing agents to develop mesochannels. We propose viable approach to use novel mesoporous glasses as drug delivery vehicles and 3-D scaffold matrix for the tumor infected bones. The emphasis has been given on loading anticancerous, analgesic and antibacterial drugs simultaneously into the mesochannels, to obtain the effect of combined loading on release capability of MBGs. The innovation behind this approach is to heal any inflammatory response /bacterial infection apart from killing the infected malignant cells. The 3-D scaffolds of MBGs are further used for the bone regeneration or healing at the tumour infected sites. Bone-tissue engineering combines progenitor cells, such as mesenchymal stem cells or mature cells (for osteogenesis) seeded in biocompatible scaffolds (for osteoconduction and vascular ingrowth), with appropriate growth factors, in order to generate and maintain bone. |