| Abstract Scope |
Musa Ayran, Kubra Aranci, Yigit Turan, Songul Ulag, Oguzhan Gunduz
This study aims to develop Gelatin Methacryloyl (GelMA)-based symblepharon rings with added L-ascorbic acid (Vc) and controlled release of vitamin for the treatment of ocular surface, corneal healing, and epithelial growth acceleration, while also preventing possible inflammation. This innovative approach facilitated the production of rings that exhibit superior flexibility and softness, and are amenable to the mechanical movements of the patient. As a result, the patient's discomfort and potential complications were alleviated, thereby enhancing the clinical outcomes of the treatment .Moreover, it was shown that GelMA hydrogel can be produced by 3D printing, which promotes epithelialization, is mechanically compatible with epithelial tissue, and provides a moist environment. Furthermore, the produced symblepharon rings possessed unique values, display innovative approaches and contribute new data to the literature.
Keywords: Symblepharon rings; GelMA; L-ascorbic acid, DLP technology; cornea. |