| About this Abstract |
| Meeting |
2020 TMS Annual Meeting & Exhibition
|
| Symposium
|
Biological Materials Science
|
| Presentation Title |
B-18: Modulation of Neurogenic Differentiation by Reinforcement of Polymeric Scaffolds with Different Carbon Nanofillers |
| Author(s) |
Souvik Ghosh, Swati Haldar, Viney Kumar, Partha Roy, Debrupa Lahiri |
| On-Site Speaker (Planned) |
Souvik Ghosh |
| Abstract Scope |
Regeneration and differentiation of neuronal cells are required for treating various neurological disorders and can be achieved through neural tissue engineering.Electrical impulses are needed for neural regeneration and differentiation.Available options either do not have the provision for electrical cues or they require high end techniques for synthesis.This study approaches towards synthesis of inexpensive and easy to tailor neural scaffold.In this study the fabrication and characterization of composite scaffold reinforced with either multi-walled carbon nanotubes (MWCNTs) or graphene nanoplatelets (GNPs) was described.These reinforcements were aligned along particular directions to impart anisotropic conductivity to the scaffolds.The scaffolds promoted cell differentiation in the presence of electrical field. Interestingly, structural differences of the carbon nanofillers dictated the morphology of growing neurons: elongated in case of MWCNTs and astral for GNPs. Differences achieved in the morphology of the neurons through different nanofillers create options of using these scaffold in both PNS and CNS tissue engineering. |
| Proceedings Inclusion? |
Planned: Supplemental Proceedings volume |