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Meeting 2025 TMS Annual Meeting & Exhibition
Symposium Mechanics and Physiological Adaptation of Hard and Soft Biomaterials and Biological Tissues
Presentation Title Assessing molar incisor hypomineralisation through multiscale imaging and analytics
Author(s) Bjorn Busse
On-Site Speaker (Planned) Bjorn Busse
Abstract Scope Molar Incisor Hypomineralisation (MIH) is a developmental dental condition characterized by rapid tooth decay due to hypomineralized enamel. This condition, which affects about 15% of children worldwide, results in pain and frequent cavities. The causes of MIH are still unknown and speculative, hindering the development of effective treatment regimens and potential prevention strategies. High-resolution imaging and analytical methods, including vibrational spectroscopy and scanning electron microscopy with Focused Ion Beam (FIB)-tomography, have been used to elucidate the composition and quality of the mineral and protein constituents of MIH-affected teeth. Additionally, biomechanical characterization of MIH teeth has been conducted to understand material flaws. We provide insights into the microstructural, compositional, and cellular indices that may play a role in the pathophysiology of MIH.
Proceedings Inclusion? Planned:
Keywords Biomaterials, Characterization, Composites

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

Advances in Bone Research – 60 Years of Progress
Assessing molar incisor hypomineralisation through multiscale imaging and analytics
Convergent Evolution to Engineering: Blueprints for Multifunctional Advanced Materials
Development of novel mechanochemically active hydrogels
Dynamically-Driven Osteoblast Attachment and Stress Fiber Formation on 4D Nanoarchitected Scaffold-on-Chip
Effects of Zinc Deficiency and Arsenic Co-Exposure on Bone in Growing Female Mice
Experimental Model of a Pore as a Valve Mechanism
Exploring the Effects of Disease on Teeth: Mouse Models of Type 1 and Type 2 Diabetes
Impact of heavy alcohol consumption on cortical bone mechanical properties in male rhesus macaques
Impact of Type 2 Diabetes on the Lacunar Canalicular Network in Cortical Bone: A Connectomic Analysis
Insights to Enhance Toughness of Human Bone through Nanoscale Deformation and Fracture Analysis
Investigations on Mechanical Properties and Multi-functionalities of 3D-printed, Denticle-like Composites Inspired by the Skin of Slow-swimming Catshark
Multi-scale adaptation of bone in health and disease
Multi-scale fracture resistance of young brittle bones treated with bisphosphonates
Sustainable innovation – learning from nature’s grippers and stingers
The hierarchical design of the echinoid skeletal structure: structural, compositional and crystallographic variability in relation to the regional micromechanical function
The Osteoinductive Capacity of Demineralized Allogenic Bone Matrix Is Impaired By Chronic Heavy Alcohol Consumption
Understanding Self-Sharpening Mechanism of Sea Urchin Tooth via Nanostructural and Nanomechanical Mapping
Understanding the impact physiologically relevant stressors on the structure and properties of fungi
Zone-Specific Flocking of Zinc and Sulfur in the Temporomandibular Joint

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