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Meeting 2025 TMS Annual Meeting & Exhibition
Symposium Mechanics and Physiological Adaptation of Hard and Soft Biomaterials and Biological Tissues
Presentation Title Assessing molar incisor hypomineralisation through multiscale imaging and analytics
Author(s) Bjorn Busse
On-Site Speaker (Planned) Bjorn Busse
Abstract Scope Molar Incisor Hypomineralisation (MIH) is a developmental dental condition characterized by rapid tooth decay due to hypomineralized enamel. This condition, which affects about 15% of children worldwide, results in pain and frequent cavities. The causes of MIH are still unknown and speculative, hindering the development of effective treatment regimens and potential prevention strategies. High-resolution imaging and analytical methods, including vibrational spectroscopy and scanning electron microscopy with Focused Ion Beam (FIB)-tomography, have been used to elucidate the composition and quality of the mineral and protein constituents of MIH-affected teeth. Additionally, biomechanical characterization of MIH teeth has been conducted to understand material flaws. We provide insights into the microstructural, compositional, and cellular indices that may play a role in the pathophysiology of MIH.
Proceedings Inclusion? Planned:
Keywords Biomaterials, Characterization, Composites

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

Advances in Bone Research – 60 Years of Progress
Assessing molar incisor hypomineralisation through multiscale imaging and analytics
Convergent Evolution to Engineering: Blueprints for Multifunctional Advanced Materials
Development of novel mechanochemically active hydrogels
Dynamically-Driven Osteoblast Attachment and Stress Fiber Formation on 4D Nanoarchitected Scaffold-on-Chip
Effects of Zinc Deficiency and Arsenic Co-Exposure on Bone in Growing Female Mice
Experimental Model of a Pore as a Valve Mechanism
Exploring the Effects of Disease on Teeth: Mouse Models of Type 1 and Type 2 Diabetes
Impact of heavy alcohol consumption on cortical bone mechanical properties in male rhesus macaques
Impact of Type 2 Diabetes on the Lacunar Canalicular Network in Cortical Bone: A Connectomic Analysis
Insights to Enhance Toughness of Human Bone through Nanoscale Deformation and Fracture Analysis
Investigations on Mechanical Properties and Multi-functionalities of 3D-printed, Denticle-like Composites Inspired by the Skin of Slow-swimming Catshark
Multi-scale adaptation of bone in health and disease
Multi-scale fracture resistance of young brittle bones treated with bisphosphonates
Sustainable innovation – learning from nature’s grippers and stingers
The hierarchical design of the echinoid skeletal structure: structural, compositional and crystallographic variability in relation to the regional micromechanical function
The Osteoinductive Capacity of Demineralized Allogenic Bone Matrix Is Impaired By Chronic Heavy Alcohol Consumption
Tooth enamel mineralization before and after tooth eruption
Understanding Self-Sharpening Mechanism of Sea Urchin Tooth via Nanostructural and Nanomechanical Mapping
Understanding the impact physiologically relevant stressors on the structure and properties of fungi
Zone-Specific Flocking of Zinc and Sulfur in the Temporomandibular Joint

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