| Abstract Scope |
Bioinspired ceramic composites exhibit outstanding mechanical properties and are promising for application as implants. Here, the response of osteoblasts to bioinspired ceramic composites made of aluminum oxide microplatelets oriented in anisotropic patterns in ceramic or organic matrix is studied. More specifically, the cytotoxicity and differentiation of the osteoblasts to the composites and the effects of microstructure on the cells’ response are explored. The effect of iron is also looked at since ion oxide is an additive used in the processing of these materials. Finally, dental implants with properties matching those of natural teeth are proposed. Overall, all the bioinspired ceramic composites are found to be biocompatible with no cytotoxicity. The presence of iron may also increase the grow rate of the cells. Finally, cells align in the ceramic-polymer composites. The mechanical and biological properties of bioinspired ceramic composites can be similar to that of natural teeth. |