| About this Abstract |
| Meeting |
2022 TMS Annual Meeting & Exhibition
|
| Symposium
|
Biological Materials Science
|
| Presentation Title |
Nanomechanical Mapping in Bone Using Atomic Force Microscopy |
| Author(s) |
Yichun Tang, Yuxiao Zhou, Jing Du |
| On-Site Speaker (Planned) |
Jing Du |
| Abstract Scope |
Bone exhibits superior load-bearing functions, which can be attributed to its hierarchical structures. In this work, PeakForce Tapping atomic force microscopy (AFM) scans were performed on bovine cortical bone specimens submerged in water. The elastic modulus map and surface morphology were obtained for bone across multiple length scales. In the submillimeter-scale, the elastic modulus of osteons was slightly lower than that of interstitial bone. In the micro-scale, the elastic modulus in the lamella structures varied periodically from higher values in thick sub-lamellae to the lower values in thin sub-lamellae. They were both much greater than that of the cement line, which plays an important role in the fatigue and fracture of bone. In the submicron-scale, relatively softer mineralized collagen fibril bundle arrays were embedded in harder extrafibrillar matrix. The variations in the elastic modulus were discussed for the degrees of mineralization and fibril orientations. |
| Proceedings Inclusion? |
Planned: |