About this Abstract |
Meeting |
2022 TMS Annual Meeting & Exhibition
|
Symposium
|
BioNano Interfaces and Engineering Applications
|
Presentation Title |
NOW ON-DEMAND ONLY - Self-assembling Nanoclay Gels for Tissue Regeneration |
Author(s) |
Jon I. Dawson |
On-Site Speaker (Planned) |
Jon I. Dawson |
Abstract Scope |
Clay nanoparticles offer a surprisingly rich array of opportunities for biomaterial design and regenerative medicine that are only beginning to be explored. In aqueous solutions nanoclay particles self-assemble into stiff gels upon contact with physiological ionic solutions. Upon implantation in the body, nanoclay gels provide bioactive environments, through the adsorption of proteins and ions that promote the invasion of cells. Due to their affinity for proteins such as growth factors, nanoclay gels can be applied to deliver, localise, enhance and even pattern activity of growth factors to initiate tissue regeneration. This talk will describe the development and application of nanoclays for growth factor delivery and regenerative medicine including recent work to translate this technology towards a therapy for bone fusion. |
Proceedings Inclusion? |
Planned: |
Keywords |
Biomaterials, Ceramics, Nanotechnology |