| About this Abstract |
| Meeting |
MS&T24: Materials Science & Technology
|
| Symposium
|
Additive Manufacturing of Polymeric-based Materials: Potentials and Challenges
|
| Presentation Title |
Antimicrobial Coating of 3D Printed Polyetheretherketone(PEEK) Spinal Cages |
| Author(s) |
Caden Kurzenknabe, Ola H. Rashwan |
| On-Site Speaker (Planned) |
Caden Kurzenknabe |
| Abstract Scope |
Polyetheretherketone (PEEK) is a semicrystalline thermoplastic polymer used extensively in biomedical implants due to its chemical and thermal stability and mechanical properties, which are similar to those of human bones. However, PEEK has no inherent antimicrobial properties, which results in infections that threaten patients’ lives and burden the healthcare system.
This project aims to develop a uniform layer of silver nanoparticles (AgNPs) on the 3D-printed PEEK spinal cages with the aid of dispersion agents. Silver is known for its broad spectrum of antimicrobial activity and relatively low toxicity to human cells. The spinal cages are tested for antimicrobial efficacy according to the shake flask method. Furthermore, the cell viability (non-cytotoxicity) tests according to ISO-10993-5 standard are performed.
Morphological characterization, including scanning electron microscope (SEM) and transmission electron microscope (TEM), is undertaken to characterize the new antimicrobial-coated PEEK spinal cages. |