| About this Abstract |
| Meeting |
2025 TMS Annual Meeting & Exhibition
|
| Symposium
|
Advanced Biomaterials for Biomedical Implants
|
| Presentation Title |
Process Optimization and Biocompatibility of PEEK-HA-Carbon Composites |
| Author(s) |
Leila Ladani, Amir Azimi, David Lott, Brent Chang |
| On-Site Speaker (Planned) |
Amir Azimi |
| Abstract Scope |
This study investigates the biocompatibility of additively manufactured polyetheretherketone (PEEK) composites reinforced with carbon nanotubes (CNT), carbon fiber (CF), and hydroxyapatite (HA) for bone implants. While pure PEEK has many advantages, there is a need to enhance its mechanical properties and bioactivity. A design of experiment (DoE) is employed to optimize the milling of powders, single-screw extrusion, and filament fused fabrication (FFF) 3D printing or bioimplants. Parameters such as temperature, speed, and duration for each step in the manufacturing process are optimized to fabricate a porous scaffold. The microstructure and surface morphology of the scaffolds are analyzed using submicron X-ray computed tomography (XCT) and scanning electron microscopy (SEM). Mechanical testing is used to determine the strength and elasticity of composite material and to evaluate mechanical biocompatibility. In vivo testing using murine models is conducted to evaluate osseointegration and angiogenesis of the fabricated implants. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Additive Manufacturing, Biomaterials, Composites |