| About this Abstract |
| Meeting |
2023 Annual International Solid Freeform Fabrication Symposium (SFF Symp 2023)
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| Symposium
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2023 Annual International Solid Freeform Fabrication Symposium (SFF Symp 2023)
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| Presentation Title |
Materials Screening Methodology for Additive Manufacturing in Bioreactor Technology |
| Author(s) |
Johann Schorzmann, Hannes Gerstl, Zhixin Tan, Lys Sprenger, Hsuan-Heng Lu, Sarah Taumann, Marco Wimmer, Sahar Salehi-Müller, Aldo R. Boccaccini, Frank Döpper |
| On-Site Speaker (Planned) |
Johann Schorzmann |
| Abstract Scope |
Biofabrication is used to fabricate complex organs and mimic tissue structures from bio-inks (biopolymers enriched with living cells) using additive manufacturing (AM). Electroactive cells such as skeletal muscle function via electrical signals and therefore, their optimum in vitro functionality requires electrical stimulations. AM can be used to precisely fabricate a bioreactor for a dynamic culture of cells and bioengineered tissues with selective electrical conductivity and electrical stimulation of the cells. In this study, we focused on a material selection methodology for AM of bioreactors based on Reuter.
Fulfilling all material requirements, biocompatibility, chemical stability, electrical conductivity, and sterilization, are the main criteria in the fabrication of bioreactor. But there is no standardized procedure for selecting materials in AM.
Our study comprises four phases which deductively narrowed down the material selection (Phase I-IV: determination of material requirements; pre-selection of suitable materials; fine selection and assessment; evaluation/ validation of material properties). |
| Proceedings Inclusion? |
Definite: Post-meeting proceedings |