| About this Abstract |
| Meeting |
2020 TMS Annual Meeting & Exhibition
|
| Symposium
|
Mechanical Response of Materials Investigated through Novel In-situ Experiments and Modeling
|
| Presentation Title |
Synchronized Indentation and Raman Spectroscopy for Crystal Engineering |
| Author(s) |
Praveena Manimunda, Manish Kumar Mishra, Syed Asif |
| On-Site Speaker (Planned) |
Praveena Manimunda |
| Abstract Scope |
Molecular crystals offer a broad canvas for the design of advanced materials with biocompatibility and unique mechanical properties. Designing such materials demand understanding of both intermolecular interactions and crystal packings. Nanoindentation has become a state-of-the-art method to probe the mechanical properties of molecular crystals, especially pharmaceuticals. However, not as well addressed is the chemical characterization, which is equally important. In this study surface sensitive Raman spectroscopy technique was combined with instrumented indentation to probe the structural origin of elasticity in halogenated N-benzylideneanilines organic crystals. In situ Raman spectra corresponding to δ(C-Cl), aromatic asymmetric in-plane bending δ(C-H) and aliphatic C-H stretching modes revealed how intermolecular interactions such as C−H···N, C−H···Cl, C−H···Br, Cl···Cl and Br···Br perturb during bending. Further, mechanical anisotropy and mechanochemical changes during indentation on piroxicam crystal (an anti-inflammatory drug) studied using Indentation and Raman spectroscopy. |
| Proceedings Inclusion? |
Planned: Supplemental Proceedings volume |