| About this Abstract |
| Meeting |
2025 TMS Annual Meeting & Exhibition
|
| Symposium
|
Mechanics and Physiological Adaptation of Hard and Soft Biomaterials and Biological Tissues
|
| Presentation Title |
Experimental Model of a Pore as a Valve Mechanism |
| Author(s) |
Athan Sanders, Douglas H Kelley |
| On-Site Speaker (Planned) |
Athan Sanders |
| Abstract Scope |
Pores frequently occur in biological tissues. One such example is the gaps between the astrocyte endfeet that surround arteries in the brain. Flow through these pores often cause bending of the porous material. If the pore is asymmetric, then contraction and dilation of the pore in response to an oscillating fluid pressure would also be asymmetric. This asymmetry results in a naturally occurring valve mechanism. In our project, we explored the effect of pore geometry and material properties on flow rectification. We produced silicon and hydrogel membranes with a variety of pore shapes and subjected them to flows with both static and oscillating driving pressures. To investigate the effect of geometry on flow rectification we tested conical pores of different taper angles. Exploring the relationship between oscillation frequency of pressure and the material’s storage and loss modulus could allow us to extrapolate the properties of porous materials from flow measurements. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Mechanical Properties, |