| About this Abstract |
| Meeting |
2023 TMS Annual Meeting & Exhibition
|
| Symposium
|
Biological Materials Science
|
| Presentation Title |
Graphene Foam as an Active Bioscaffold for Cartilage Tissue Engineering |
| Author(s) |
Mone't Sawyer, Michael Eppel, Olivia Nielson, Josh Eixenberger, Raquel Montenegro-Brown, David Estrada |
| On-Site Speaker (Planned) |
Mone't Sawyer |
| Abstract Scope |
Knee osteoarthritis (OA) is a progressive musculoskeletal disorder that results from the damage or wear of hyaline cartilage found at the surface of articulating joints. Once damage occurs, articular cartilage has a limited capacity to repair itself, and when repair tissue is formed, it is mechanically inferior to its healthy counterpart. Three-dimensional tissue engineering (TE) is a prospective treatment that can be used to restore or replace these damaged tissues, however, current challenges include identifying materials that are biocompatible and have properties that imitate the mechanical properties and cellular environment of the target tissue. Due to their excellent electrical, mechanical, and thermal properties, graphene foam (GF) bioscaffolds have the ability to overcome this gap in tissue engineering. This work investigates the role that GF has as an electrically active bioscaffold for ATDC5 cell culture, proliferation, differentiation, ECM matrix production, and on the resultant mechanical properties of the GF-tissue composite. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Additive Manufacturing, Biomaterials, Other |