| About this Abstract |
| Meeting |
2024 TMS Annual Meeting & Exhibition
|
| Symposium
|
Bio-Nano Interfaces and Engineering Applications
|
| Presentation Title |
Tailoring the Micro- and Nanostructure of Freeze-cast Scaffolds for Biomaterials |
| Author(s) |
Steven E. Naleway, Tony Yin, Maddie Schmitz, Josh Fernquist, Debora Lyn Porter, Elise Hotz |
| On-Site Speaker (Planned) |
Steven E. Naleway |
| Abstract Scope |
Freeze casting is a bioinspired technique for the fabrication of tailored, porous ceramic materials with structuring down to the nanoscale. Mimetic of the growth of mammalian bone and other biomaterials where biopolymers template the deposit of biominerals to create complex composites, freeze casting employs a template of growing ice crystals to create a complex porous microstructure in any ceramic. We propose that this bioinspired technique can be controlled through either intrinsic (those that modify from within by altering the constituents) or extrinsic (those that apply external forces or templates) means. Through these classifications, examples of extrinsic (through energized external fields) freeze cast, bioinspired structures will be discussed with a focus mimicking the structure of natural bone and, in particular, impacting the nano-scale interface of the synthetic so as to improve cell adhesion. In vitro results and applications as bone filler materials will be discussed. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Ceramics, Additive Manufacturing |