| About this Abstract |
| Meeting |
2021 TMS Annual Meeting & Exhibition
|
| Symposium
|
Bio-Nano Interfaces and Engineering Applications
|
| Presentation Title |
Flexible-glass Like Coating onto PTFE Vascular Graft Material via Nonthermal Plasma Process |
| Author(s) |
Vineeth Vijayan, Bernabe S Tucker, Yogesh Vohra, Vinoy Thomas |
| On-Site Speaker (Planned) |
Vinoy Thomas |
| Abstract Scope |
PTFE is a fluoropolymer that is widely used as a vascular graft substitute in cardiovascular and hemodialysis applications, but only for large- and medium-diameter PTFE vascular grafts. For small-diameter PTFE vascular grafts, there are considerable risks for thrombosis – blood clotting – and a lack of endothelial cell growth and associated intimal hyperplasia. Non-thermal plasma-polymerized hydrophilic glass-like coating provided a blood compatible material interface. Spectral and microscopic analyses were carried out for the coating characterization. The augmented PTFE surfaces demonstrate better endothelial cell adhesion and reduced platelet adhesion without changing the mechanical flexibility of the graft.According to the American Society of Nephrology more than 300,000 Americans have end-stage renal disease and are depending on artificial dialysis to stay alive. In the context of COVID-19, there are increased cases in the number of ICU dialysis patients due to severe kidney infections and blood clots. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Surface Modification and Coatings, Polymers |