| About this Abstract |
| Meeting |
2025 TMS Annual Meeting & Exhibition
|
| Symposium
|
2025 Technical Division Student Poster Contest
|
| Presentation Title |
SPG-29: Towards Low-Temperature Additive Manufacturing Process for Miniaturized Disposable Antibody-Type Biosensor |
| Author(s) |
Elizabeth D. Clark, Enrico Condemi, Philippe A. Passeraub |
| On-Site Speaker (Planned) |
Elizabeth D. Clark |
| Abstract Scope |
In vitro diagnostic tools are being developed to rapidly detect diseases and biomarkers without the need for complex laboratory techniques. Pad printing is emerging as a low-temperature manufacturing method to create disposable electrode biosensors from thin layers of silver and carbon-based inks. This work seeks to miniaturize such pad-printed carbon-based electrodes (PPCE) to improve their sensitivity and fit more sensors on a single test strip. Each PPCE was fabricated by printing layers of silver ink, cured with a rapid near-infrared drying process, followed by printing carbon ink layers. The PPCEs were then cured in an oven at 80°C prior to testing with cyclic voltammetry and electrochemical impedance spectroscopy. Preliminary results show biomarker detection in the pg/ml range. The effect of miniaturization on sensitivity is being studied with the perspective of making multiplex point-of-care diagnostic devices. Future work will focus on attaching antibodies to the PPCEs for rapid biomarker detection. |
| Proceedings Inclusion? |
Undecided |
| Keywords |
Additive Manufacturing, Thin Films and Interfaces, Other |