| About this Abstract |
| Meeting |
2024 TMS Annual Meeting & Exhibition
|
| Symposium
|
Biological Materials Science
|
| Presentation Title |
Conductive Graphene Foam Bioscaffolds Facilitate Direct Electrical Stimulus for Cartilage Tissue Engineering |
| Author(s) |
Mone't Sawyer, Olivia Nielson, Hailey Burgoyne, Katelyn Wada, Michael Eppel, Raquel Montenegro-Brown, Josh Eixenberger, David Estrada |
| On-Site Speaker (Planned) |
Mone't Sawyer |
| Abstract Scope |
Articular cartilage (AC) damage is a frequent occurrence that can lead to osteoarthritis. Tissue engineering aims to repair these damaged tissues; however, human tissues are complex in function, structural hierarchy, and scale, making it difficult to synthesize functional tissue. Over the last decade, AC tissue engineering has evolved from 2D cell cultures grown on planar surfaces to complex 3D architectures. The goal with 3D bioscaffolds is to mimic the environment of AC as it is known that the material properties of bioscaffolds can drive cell behaviors leading to tissue formation. Graphene foam (GF) is a porous substrate with unique material properties that can be harnessed to drive cell behavior by facilitating the delivery of localized physical cues to stimulate tissue growth. This study investigates the effect that in vitro electrical stimulus applied to chondrocyte progenitor cells cultured on GF has on cell behavior and the mechanical properties of GF-tissue constructs. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Additive Manufacturing, Other |