About this Abstract |
Meeting |
MS&T23: Materials Science & Technology
|
Symposium
|
Next Generation Biomaterials
|
Presentation Title |
Polycaprolactone-based Polymerized High Internal Phase Emulsions with Bioceramic Inclusions |
Author(s) |
Sierra K. Kucko, Timothy Keenan |
On-Site Speaker (Planned) |
Sierra K. Kucko |
Abstract Scope |
Polycaprolactone (PCL) is a polymer utilized extensively in tissue engineering. Advanced polymeric chemistries enable PCL to be functionalized with end-groups that are photocurable. This photopolymerization holds immense possibility, as it is well-suited to combination with other light-based fabrication processes. Polymerized high internal phase emulsions (polyHIPEs) developed with such photocurable PCL can be cured almost instantaneously to create tailorable scaffolds that are highly porous and interconnected. Polymer chemistry reactions are described, and the chemical constituents of the functionalized PCL pre-polymer is analyzed through Raman and ATR-FTIR spectroscopy. Porosity and interconnectivity of the polymerized construct are demonstrated with SEM imaging. The feasibility of bioceramic particle incorporation into the described PCL-based polyHIPE is explored with preliminary characterization of this proof-of-concept next-generation bio-composite. |