| Abstract Scope |
For many years, there has been a discussion if topography of a surface would be more important than its chemical composition to promote tissue integration of a biomaterial. For osteointegration, it seemed that micro rugosity played a key role on ceramic and metallic biomaterials. On the other hand, for applications that required interactions with other types of cells (soft tissues or blood), other factors (like biopolymer loops and tails) played a more important role for specific devices performance (eg. sensors). In any applications, such as scaffolds, bioceramics, biomimetic materials, sensors, etc understanding how surface modification of biomaterials affects the interactions with living cells is capital. In this work, we discuss these factors under the light of the types of biomaterials that our group has been studied, from calcium phosphate-based materials, hybrid materials and natural polymer coated devices. |