| About this Abstract |
| Meeting |
MS&T23: Materials Science & Technology
|
| Symposium
|
Next Generation Biomaterials
|
| Presentation Title |
Better Osteogenesis of Electrically Active Hydroxyapatite-Calcium Titanate Biocomposites in a Rabbit Animal Model |
| Author(s) |
Prafulla Kumar Mallik, Bikramjit Basu, Kantesh Balani |
| On-Site Speaker (Planned) |
Prafulla Kumar Mallik |
| Abstract Scope |
HA is a highly biocompatible and bioactive materials used for variety of biomedical applications. However, HA has very poor electrical conductivity and inherent brittleness. Recently, CaTiO3 has been proved its better biocompatibility, polarisation and bioactive material compared to HA. The electrical properties of spark plasma sintered HA-CaTiO3 composites was studied using impendence analyser and was determined their effect on osteogenesis and osteointegration with living tissue using rabbit animal model. Subsequently, biocompatibility and its percentage neobone formation were estimated in vivo using histological and histomorphometrical analysis. As result, the AC conductivity of HA-80%CaTiO3 posses enhanced biocompatibility and better osteointegration after 12 weeks of implantation in rabbit compared to HA by addition of CaTiO3. Finally, it could be suggested that HA-80%CaTiO3 improving its potential for clinical application. |