About this Abstract |
Meeting |
MS&T24: Materials Science & Technology
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Symposium
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3D Printing of Biomaterials and Devices
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Presentation Title |
Hybrid Peptides for Multi-Functional Heterogeneous Interfaces |
Author(s) |
Candan Tamerler |
On-Site Speaker (Planned) |
Candan Tamerler |
Abstract Scope |
Biomolecules are essential in physiological processes, and smaller molecules such as peptides offer to mimic their function to be uniquely versatile molecular tools in coupling biologically instructive roles in heterogenous interfaces and biomaterials. Our group has been exploring peptides as the key fundamental building blocks that guides the bio-hybrid interfacial interactions in functional bio-hybrid material designs. These peptides can be coupled into different formulations to be deployed on the site or as part of the biofunctionalization molecular tools as well as utilized as an integral component of multiple bioink combinations in the presence of other components. We incorporated machine learning (ML) methods to capture distinct peptide functionalities as elements of critical modular building blocks, and expand the functional domains to design peptides for peptide-metal and peptide-polymer hybrids as well as developed models for allosteric-dependent effects of selecting spacers to add multiple functionalities to address heatlh and technology applications.
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