About this Abstract |
Meeting |
2022 TMS Annual Meeting & Exhibition
|
Symposium
|
BioNano Interfaces and Engineering Applications
|
Presentation Title |
3D Printing for Bone Regeneration: Convergence of Knowledge |
Author(s) |
Susmita Bose |
On-Site Speaker (Planned) |
Susmita Bose |
Abstract Scope |
3D printing (3DP) or additive manufacturing (AM) is important in clinical needs for on-demand patient-matched implants due to better functionalities. Establishing process property relationships for different AM techniques is vital to their successful implementation in biomedical devices. AM of multiple materials in a single operation is also an exciting innovation. Hard biomaterials, e.g., calcium phosphate (CaP) ceramics being compositionally similar to the inorganic part of the bone, are often used in bone implants, as both 3DP tissue engineering scaffolds and surface modified hip and knee implant devices. We have used 3DP CaP scaffolds, for bone tissue engineering, where 3D interconnected channels in CaP scaffolds provide pathways for micronutrients transport and improved mechanical interlocking between scaffolds and surrounding bone. In vivo studies show improved osteogenesis, angiogenesis, and controlled drug delivery using natural medicinal compounds (NMCs) in these 3DP scaffolds and coatings demonstrating promise for their use in orthopedic and dental devices. |
Proceedings Inclusion? |
Planned: |
Keywords |
Biomaterials, Additive Manufacturing, Surface Modification and Coatings |