| About this Abstract |
| Meeting |
2025 TMS Annual Meeting & Exhibition
|
| Symposium
|
Biological Materials Science
|
| Presentation Title |
Mucosa-Interfacing Capsule Robot for In Situ Sensing
the Elasticity of Biological Tissues |
| Author(s) |
Xiaoguang Dong |
| On-Site Speaker (Planned) |
Xiaoguang Dong |
| Abstract Scope |
Monitoring the elasticity of soft biological tissues in the gastrointestinal (GI) tract with minimal invasion holds promise for early diagnosis of intestinal fibrosis, colorectal cancer, and other diseases featuring abnormal elasticity. However, existing methods of sensing tissue elasticity have drawbacks such as insufficient resolution for elastography, and discomfort or the requirement of risky anesthesia for flexible endoscopes or implantable devices. We present a wirelessly actuated palpation mechanism integrated into a swallowable capsule robot, offering in situ tissue elasticity measurement with minimal invasiveness. Our approach employs a magnetic soft cantilever beam actuated by external magnetic fields to gently press against soft tissue. Mechanical stress and strain are monitored by an onboard magnetic sensor and a strain gauge. We validate the elasticity sensing mechanism on both phantom structures and ex vivo porcine colon tissues. Our capsule robot could allow monitoring tissue properties for early disease diagnosis in hard-to-reach areas of the body. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Electronic Materials, Characterization |