| About this Abstract |
| Meeting |
2023 TMS Annual Meeting & Exhibition
|
| Symposium
|
Biological Materials Science
|
| Presentation Title |
Novel Zn-Cu-Al-TiC Nanocomposites for Biodegradable Stent Application |
| Author(s) |
Yuxin Zeng, Chase S. Linsley, Jingke Liu, Benjamin M. Wu, Xiaochun Li |
| On-Site Speaker (Planned) |
Yuxin Zeng |
| Abstract Scope |
Zn has emerged as a promising material for biodegradable medical devices due to its excellent biocompatibility and corrosion rate. It has commonly been alloyed with other elements to overcome its intrinsically low strength. Although moderate mechanical properties and corrosion rate have been achieved, issues such as fatigue and creep have rarely been studied. Prior research has shown that nanoparticles can boost the fatigue performance and thermal stability of Zn alloys. In this study, TiC nanoparticles were introduced into Zn for the first time. With nanoparticles and refined intermetallic phases, the tensile strength of hot-rolled Zn samples is increased while maintaining a moderate ductility. Additionally, cytotoxicity and immersion testing revealed good biocompatibility and corrosion rate. Fatigue performance was also evaluated, suggesting that nanoparticles served as barriers to crack propagation for longer service life. These results suggest that our novel Zn-Cu-Al-TiC nanocomposites can be suitable for application in biodegradable stents. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Mechanical Properties, Nanotechnology |