| About this Abstract |
| Meeting |
2023 TMS Annual Meeting & Exhibition
|
| Symposium
|
Mechanics and Physiological Adaptation of Hard and Soft Biomaterials and Biological Tissues
|
| Presentation Title |
Adaptation of Hard and Soft Tissues Structures to Physiological Loading Patterns |
| Author(s) |
Elizabeth Zimmermann |
| On-Site Speaker (Planned) |
Elizabeth Zimmermann |
| Abstract Scope |
Bones have the capability to adapt their shape, size and potentially their material properties to their mechanical environment: as mechanical strain on bone decreases, bone is resorbed, as mechanical strain increases, bone is formed. Most studies investigate bone adaptation through the lens of exercise or loading regimes targeting osteogenic strain levels. My research program seeks to understand the role of soft tissues, like muscles and ligaments, on bone adaptation. One classic example is cerebral palsy, where abnormal muscle tone can lead to abnormal function, bone deformities and fracture risk. The effects of cerebral palsy on bone are especially dramatic because the abnormal muscle tone and movements are applied to growing bones. Another example is the periodontal ligament, which anchors the tooth to the alveolar bone. It is unknown how the morphology of the periodontal ligament and its connection to the surrounding bone vary based on different mechanical environments. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Mechanical Properties, Characterization |