| About this Abstract |
| Meeting |
MS&T22: Materials Science & Technology
|
| Symposium
|
Society for Biomaterials: Biological Response to Materials and Material’s Response to Biological Environments
|
| Presentation Title |
Scalable Green Electrospinning of an Environmentally Safe Nanofibrous Fish Skin Gelatin Material for a Sustainable Tissue Replacement Bank |
| Author(s) |
Amanda J. Kennell, Olivia Shivers, Ma Halog, Ranoah Holcomb, Courtney Severino, Andrei Stanishevsky |
| On-Site Speaker (Planned) |
Amanda J. Kennell |
| Abstract Scope |
An inexpensive, environmentally friendly biomaterial that can be mass produced on demand would be beneficial for the patients that need an organ transplant. This study focuses on utilizing fish skin gelatin (FSG) which has demonstrated a strong potential for this natural nanofibrous biomaterial bank. A high throughput alternating field electrospinning (AFES) techniques has been used to fabricate uniform FSG nanofibers with an average diameter of under 200 nm from pure aqueous solutions at 12.6 g/h production rate that can be further increased to a commercially feasible level. Several natural additives and cross-linking protocols of the nanofibrous FSG material have been tested to tailor the mechanical properties and degradation rates of fabricated nanofibrous FSG material in a physiological environment. Further testing of the material shows that naturally fluorescent tdTomato fibroblasts, have a potential for live imaging, proliferated across the nanofibrous FSG biomaterial in all making it an ideal biomaterial. |