| About this Abstract |
| Meeting |
2022 TMS Annual Meeting & Exhibition
|
| Symposium
|
BioNano Interfaces and Engineering Applications
|
| Presentation Title |
Sensing of COVID-19 Antibodies and Antigens in Seconds via Aerosol Jet Nanoprinted Reduced Graphene Oxide Coated Three Dimensional Electrodes |
| Author(s) |
Md. Azahar Ali, Chunshan Hu, Sanjida Jahan, Bin Yuan, Mohammad Sadeq Saleh, Fei Zhang, Shou-Jiang Gao, Rahul Panat |
| On-Site Speaker (Planned) |
Md. Azahar Ali |
| Abstract Scope |
Rapid diagnosis is critical for the treatment and prevention of diseases. We report an advanced nanomaterial-based biosensing platform that detects antibodies and antigens specific to SARS-CoV-2 within seconds. The biosensing platform is created by 3D nanoprinting of a three-dimensional electrode, coating the electrode by nanoflakes of reduced graphene oxide (rGO), and immobilizing specific viral proteins on the rGO nanoflakes. The electrode is then integrated with a microfluidic device and used in a standard electrochemical cell. Limit-of-detection of 2.8 fM was achieved via this method and read by a smartphone-based user interface. Human tests are also carried out that validate this technique. The detection time of 11.5 seconds is achieved. The sensing is highly selective, and the proposed sensing platform is generic and can be used for the rapid detection of biomarkers for other infectious agents such as Ebola, HIV, and Zika, which will benefit the public health. |
| Proceedings Inclusion? |
Planned: |