About this Abstract |
Meeting |
2023 TMS Annual Meeting & Exhibition
|
Symposium
|
Advanced Biomaterials for Biomedical Implants
|
Presentation Title |
Real-time Raman Spectroscopy of Binder Setting in Bioactive Glass Composite Bone Tissue Scaffolds |
Author(s) |
Marzieh Matinfar, John Nychka, Kalan Kucera |
On-Site Speaker (Planned) |
Kalan Kucera |
Abstract Scope |
Bioactive glasses (BAG) exhibit the unique ability of bone bonding. However, processing them into 3D porous bone scaffolds remains a challenge. Based on our proof-of-concept work, this study aims to develop a new processing route to create a formable composite scaffold composite by mixing 45S5 BAG powder and a sodium silicate binder solution, which self-sets in air. The self-setting reaction is sluggish, so three different methods were investigated to accelerate the binder setting time through acid catalysis: CO2 gas; boric acid; and phosphoric acid, which reduced setting times from 10 days to 2-20 minutes. The binder setting reaction mechanism, and the kinetics of conversion of silicate species during setting were monitored using in-situ, real-time time Raman spectroscopy. The setting time obtained by each acid catalyst was measured and a predictive model was developed. Finally, the effect of addition of BAG on the binder setting time was investigated. |
Proceedings Inclusion? |
Planned: |
Keywords |
Biomaterials, Characterization, Composites |