| About this Abstract |
| Meeting |
2025 TMS Annual Meeting & Exhibition
|
| Symposium
|
Advances in Biomaterials for Bioink Formulation and 3D Printing of Scaffolds
|
| Presentation Title |
High-Speed Embedded Ink Writing of Anatomic-Level Organ Constructs |
| Author(s) |
Yifei Jin |
| On-Site Speaker (Planned) |
Yifei Jin |
| Abstract Scope |
Current embedded ink writing (EIW) is limited to a printing speed of about 10 mm/s due to suboptimal rheological properties of particulate-dominated yield-stress fluids when used as liquid baths. In this work, we develop a particle-hydrogel interactive system to design advanced baths with enhanced yield stress and extended thixotropic response time for realizing high-speed EIW. In this system, the interactions between particle additive and three representative polymeric hydrogels enable the resulting nanocomposites to demonstrate different rheological behaviors. Accordingly, the interaction models for the nanocomposites are established, which are subsequently validated by macroscale rheological measurements and advanced microstructure characterization techniques. To demonstrate the effectiveness of the proposed high-speed EIW method, an anatomic-size human kidney construct is successfully printed at 110 mm/s, which only takes around 4 hr. This work breaks the printing speed barrier in current EIW and propels the maximum printing speed by at least 10 times. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Additive Manufacturing, Characterization |