| About this Abstract |
| Meeting |
2022 TMS Annual Meeting & Exhibition
|
| Symposium
|
Functional Nanomaterials: Functional Low-Dimensional (0D, 1D, 2D) Materials 2022
|
| Presentation Title |
Optically Active Nanoparticles in Protein Corona Studies |
| Author(s) |
Max Anikovskiy |
| On-Site Speaker (Planned) |
Max Anikovskiy |
| Abstract Scope |
Nanoparticles continue conquering the fields of drug delivery and diagnostics. However, their engineered properties become altered the moment they enter the biological milieu due to protein deposition on their surface. This process has become known as protein corona formation and has been investigated for individual proteins. However, these studies do not consider possible competition between different proteins in the body. For instance, questions remain as to what happens to nanoparticles when they transition from blood into an extracellular matrix and vice versa. This talk will focus on how optically active nanoparticles can be used to investigate the dynamic nature of protein corona formation. Furthermore, approaches to spectroscopic data analysis in order to characterize the protein corona quantitatively will be discussed. |
| Proceedings Inclusion? |
Planned: |