| Abstract Scope |
The demand for scalable manufacture of sustainable biomaterials drives the exploration of innovative technologies. Inverted pressure spinning has emerged as a promising strategy, revolutionizing the manufacture of small-structure biomaterials with exciting efficiency and a facile process. This study uses natural cellulose (plant-derived and animal waste-derived) and alginate as exemplars to explore the potential of inverted pressure spinning in biomaterials processing, elucidating its principles, advantages, system parameters, and biomedical application prospects. Physically driven by centrifugal force and assisted by high-pressure nitrogen gas flow, inverted pressure spinning enables the spinning of polymer solutions with tailored viscosity, thereby affording precise control over morphology, encompassing films, ribbons, and fibers. This processing procedure not only aligns with environmental sustainability goals but also exhibits significant scalability, thereby promoting the industrial-scale processing of biomaterials and the realization of their diverse commercial applications, thereby holding promise in advancing biomaterial manufacture and applications towards a new generation. |