| About this Abstract |
| Meeting |
2023 TMS Annual Meeting & Exhibition
|
| Symposium
|
Biological Materials Science
|
| Presentation Title |
Antibacterial Activity of Chitosan-based Spiky Gold Nanoparticles-hydrogel |
| Author(s) |
Cynthia Sangang, Jenny Qiu |
| On-Site Speaker (Planned) |
Cynthia Sangang |
| Abstract Scope |
Staphylococcus aureus is one of the major bacteria that cause diseases in humans. It is the primary cause of infections which negatively impact the immune system, often resulting in wounds. Hydrogels have been widely studied as suitable wound dressing candidates that promote rapid wound healing as they can sustain a moist wound environment while also allowing oxygen to permeate and cool the infected area. An ideal wound dressing should thus exhibit efficient antimicrobial properties. Chitosan is a naturally occurring polymer that has been commonly used as an ideal wound dressing agent owing to its good water absorption, antibacterial activity, biocompatibility, noncytotoxicity, and more. Spiky gold nanoparticles (SAuNPs) with localized surface plasmon resonance (LSPR) of up to 1320 nm were successfully synthesized and integrated into a chitosan-based hydrogel. TEM and UV-Vis-NIR confirmed the size, morphology, and absorbance peak of the SAuNPs. The antimicrobial activity of the SAuNPs-chitosan hydrogel is reported herein. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Polymers, Other |