| About this Abstract |
| Meeting |
2025 TMS Annual Meeting & Exhibition
|
| Symposium
|
Bio-Nano Interfaces and Engineering Applications
|
| Presentation Title |
3D Printed Scaffolds with Metal Nanoparticles as Sensing Modalities |
| Author(s) |
Nate Lucas, Taylor Bader, Candan Tamerler |
| On-Site Speaker (Planned) |
Nate Lucas |
| Abstract Scope |
The field of bioinks for 3D printing is advancing, with an emphasis on scaffold functionalization using bioactive molecules. We have developed a low-cost, customizable 3D bioprinter that integrates multiple bioinks with peptides possessing targeted bioactive properties for precise spatial distribution. Our printed scaffolds utilize bioinks containing gold or silver nanoparticles and binding peptides, which are evaluated for their specific bioactivity and biosensing capabilities. Silver nanoparticles (AgNPs) offer benefits such as antimicrobial activity, wound and bone healing, cancer therapy, and other biomedical applications. In contrast, gold nanoparticles (AuNPs) can act as biosensors for biomolecules and serve as targeted nano vehicles for gene and drug delivery. Previously, our lab’s research has shown that flavoprotein putrescine oxidase enhanced by gold-binding tags can self-assemble on gold surfaces, enhancing association and maintaining catalytic activity. Incorporating these materials into our bioink and testbed system, our results show promising potential in amplifying AuNP and AgNP biomedical systems. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Characterization, Additive Manufacturing |