| About this Abstract |
| Meeting |
2025 TMS Annual Meeting & Exhibition
|
| Symposium
|
Advanced Biomaterials for Biomedical Implants
|
| Presentation Title |
A Plasma-3D Print Duo Platform for Reliable Materio-Biological Screening In Vitro |
| Author(s) |
Vinoy Thomas |
| On-Site Speaker (Planned) |
Vinoy Thomas |
| Abstract Scope |
Materiobiology is an emerging field focused on the physiochemical properties of biomaterials concerning biological outcomes which includes but is not limited to the biological responses and bioactivity of surface-modified biomaterials. Gold or silica nanoparticles were deposited using two low-temperature plasma-assisted processes namely plasma electroless reduction (PER) and dusty plasma onto 3D-printed scaffolds. Materiobiological testing began with nanoparticle surface modification optimization on 96 well plate design 3D scaffolds. The in vitro assays were performed utilizing an osteosarcoma (MG-63) cell as a model. Subsequently, we performed different in vitro assays such as cell viability, and fluorescent staining of cytoskeletal actin and DNA incorporation. Furthermore, the mineralization and protein adsorption experiments conducted on 96 well plate design scaffolds have shown enhanced mineralization and bovine serum albumin adsorption for the gold nanoparticle-modified scaffolds compared to the control scaffolds. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Surface Modification and Coatings, Composites |